Mouth cancer can start in different parts of the mouth, including the lips, gums or soft sides of the mouth. Oropharyngeal cancer starts in the oropharynx. The oropharynx is the part of the throat (pharynx) just behind the mouth. Oropharyngeal cancer includes tonsil cancer and cancer in the back part of the tongue.

If your cancer started on your tongue or tonsils, you might also find it useful to look at our information about these cancers in the head and neck section.

What is mouth and oropharyngeal cancer?

Mouth and oropharyngeal cancer develops when abnormal cells in the mouth and oropharynx divide and grow uncontrollably.

Symptoms of mouth and oropharyngeal cancer

Symptoms of mouth and oropharyngeal cancer include a mouth ulcer that doesn't heal or a swelling or lump in the neck. 

Getting diagnosed with mouth and oropharyngeal cancer

Your GP will ask you about your symptoms and they might examine you. They may arrange tests or a referral to a specialist.

Survival for mouth and oropharyngeal cancer

Survival depends on many factors including the stage and grade of your cancer. 

Treatment for mouth and oropharyngeal cancer

Your treatment depends on where in your mouth or oropharynx your cancer is, the type, how big it is, whether it has spread anywhere else in your body and your general health. 
 

Stages, types and grades for mouth and oropharyngeal cancer

The stage of a cancer tells you about its size and whether it has spread. The type means the type of cell the cancer started from. The grade means how abnormal the cells look under the microscope.

Risks and causes of mouth and oropharyngeal cancer

We don't know what causes most mouth or oropharyngeal cancers. But there are some factors that can increase your risk of developing it. 

Advanced mouth and oropharyngeal cancer

Advanced mouth and oropharyngeal cancer is cancer that started in the mouth or oropharynx and has spread to another part of the body. 

Research and clinical trials for mouth and oropharyngeal cancer

All treatments must be fully researched before they can be adopted as standard treatment for everyone.

Living with mouth and oropharyngeal cancer

Getting practical and emotional support can help you cope with your diagnosis, and life during and after treatment.

Last reviewed: 
08 Jul 2024
Next review due: 
08 Jul 2027

Page Credits

This section has been written, reviewed and updated by Cancer Research UK’s Patient Information Web Team. Thanks to the expert medical professionals from the Liverpool Head and Neck Centre who have helped to review this information.

Professor Richard Shaw (Professor of Head and Neck Surgery)
Mr Jason Fleming (Consultant Head and Neck/Thyroid Surgeon)
Lesley Dempsey (Head and Neck Clinical Nurse Specialist)
Sally Lane (Head and Neck Clinical Nurse Specialist)
Terenence Lefebure (Head and Neck Clinical Nurse Specialist)
Professor Jo Patterson (Professor of Head and Neck, and Speech and Language Therapy)
Professor Andrew Schache (Consultant Oral and Maxillofacial Surgeon)
Dr Rachel Brooker (Consultant Oncologist)